Prevention and Treatment of Effects of Aging and Age-Associated Disorders with Ketone Supplementation

Tech ID: 20A012

Advantages

  • Reduces muscle atrophy and cachexia without requiring caloric restriction or fasting diets.
  • Lowers inflammation and inflammatory markers, supporting faster recovery from infections and sepsis.
  • Improves metabolic health by lowering blood glucose and balancing insulin and IGF1.
  • Eases related complications, fights tumor growth, and blends easily into everyday foods.

Summary

As the world's population ages, cardiovascular disease, neurodegeneration, and cancer are placing enormous strain on healthcare systems. Aging drives systemic inflammation, muscle loss, and catabolic wasting, yet current treatments rarely target these root processes. Patients urgently need therapies that preserve muscle mass, restore metabolic balance, and extend health span, without relying on impractical, hard to sustain interventions.

This technology is an oral ketogenic supplement that induces therapeutic ketosis without demanding strict caloric restriction or fasting, a major departure from conventional metabolic interventions. Delivered through everyday foods or dietary formulations, it lowers blood glucose, insulin, and IGF1 levels while calming the pathways that drive muscle wasting and inflammation. Because its effects do not depend on circulating anabolic hormones, it works even in complex conditions like cachexia, offering a flexible, non-toxic, and highly accessible option for patients who cannot tolerate restrictive diets.

 

 

Ketone Supplementation in an inflammation induced atrophy environment of LPS-induced sepsis (cancer independent model): KDE administration in mice reduced body weight loss (left: after 24 hours; right: up to 13 days after)

Desired Partnerships

  • License
  • Sponsored Research
  • Co-Development

Technology Transfer
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