Photo-Labels with Enhanced Ambient Light Stability and Water Solubility

Tech ID: 16A024

Competitive Advantages

  •     Ambient light stability
  •     Improved aqueous solubility
  •     Efficient in photo-labelling target proteins

Summary

Our inventors have synthesized an ambient-light stable photo-label without compromising the photo-activated insertion reactivity. The new synthesized photo-label is effective for photo-affinity labeling techniques and shows significant aqueous solubility. This invention is a significant improvement over current photo-affinity labeling reagents, and will prove useful for drug discover and studying molecular interactions.  

 

Comparison of Ambient Light Stability of Modified Trifluoromethylaryl Diazirines 1 and 2 Versus the Conventional Trifluoromethylphenyl Diazirine 3 

 

Desired Partnerships

  • License
  • Sponsored Research
  • Co-Development

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