Competitive Advantages
- Extreme pH stability
- Reversible sorption properties
- High analyte desorption efficiency
- Derivatization from traditional polymeric sorbents no longer required
- Excellent sensitivity enhancement factor
Summary
The metal oxide-based sol-gel hybrid sorbent method of production developed by our scientists overcomes the shortcomings inherent in conventional sorbents and provides a facile capillary microextraction procedure for effective extraction and enrichments of catecholamines and related molecules. Such sorbents incorporate structural and compositional features that are important for the extraction of polar analytes that require extreme pH conditions. Sol-gel hybrid sorbents offer a pH-stable alternative to conventional silica-based or organic polymer-based extraction media. Also, the various intermolecular interactions provided by the presented sorbents avoid the need for derivatization of catecholamines often required for their extraction on polymeric sorbents. These sorbents can be advantageously employed in the extraction and enrichment of catecholamines and their metabolites which represent important biomarkers for neuroendocrine tumors.
Extraction Comparison of Target Molecule Between Hybrid and Traditional Sorbents
Desired Partnerships
- License
- Sponsored Research
- Co-Development