Inhibition of aggregation of amyloidosis using cactus extracts from the Opuntia ficus indica

Tech ID: 16A068

Competitive Advantages 

  • Alternative therapy for Alzheimer's and Parkinson's disease
  • Treats underlying pathology instead of symptoms
  • Few adverse side effects

Summary

Our researchers have developed a method of treating amyloid disease found in both Alzheimer’s disease patients and Parkinson’s disease patients. They have shown that the plant mucilage extract effectively interferes with the protein accumulation pathway in the brain and successfully targets the amyloid beta protein plaques. Experimentally, both the gelling and non-gelling forms of the mucilage have been shown to disrupt the pathway leading to amyloid beta aggregation.

Effects of Extract on Aggregation Kinetics of α-Synuclein  

Desired Partnerships

  • License
  • Sponsored Research
  • Co-Development