Competitive Advantages
- Effectively inhibits ALAS
- Treats heme biosynthesis disorders and other ALAS related diseases
- Easy synthesis and purification technique
Summary
USF scientists have discovered inhibitors against 5-aminolevulinate synthase. This was achieved via a kinetic target -guided synthesis that was extended to multi-fragment screening with increased throughput. This invention provides novel molecules that are effective in treatment of diseases and metabolic disorders associated with 5-aminolevulinate synthase. It has the potential to treat heme biosynthesis disorder like porphyrias, hepatic disorders, and erythropoietic disorders.
Multi-Fragment Screening Traces and Activity
Desired Partnerships
- License
- Sponsored Research
- Co-Development