Competitive Advantages
- Causes significant reductions in tau accumulation
- May treat a variety of tauopathies
- A natural treatment option
- Compounds exhibit low toxicity and don’t alter GADPH levels
Summary
USF researchers have found that myricanol derivatives may be an effective treatment option for many neurodegenerative diseases and tauopathies including Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. This derivative has been shown to reduce aberrant overexpressed microtubule associated tau protein levels in HeLa cells. Myricanol is a known chemical compound that is isolated from the root barks of the Myrica species. Many Myrica species are edible and have been used in folk medicines for many years, proving themselves as a natural and safe treatment option.
HeLa-C3 Cells Show Decreased Tau Levels when Treated with Extracted Myricanol
Desired Partnerships
- License
- Sponsored Research
- Co-Development