Competitive Advantages
- Improved pH stability
- Higher and purer extracts yields
- Readily available materials
Summary
USF researchers demonstrated the pH stability of purely Germania-based organic-inorganic hybrid extraction media. In a further improvement, our inventors explored the properties of Germania, an isostructural analog to silica, in developing a mixed Germania-silica-based hybrid sorbent whose stationary phase closely resembles silica-based models. The resulting hybrid demonstrated a significantly improved pH stability. Furthermore, the Germania-silica sol-gel hybrid monolithic bed when combined with poly ligands and subsequently coupled to High-Performance Liquid Chromatography (HPLC) for micro-extraction, provided several ten-folds higher extraction efficiency compared with open tubular extraction columns with comparable coating composition. The invention will be useful in the chemical, pharmaceutical and biotechnology industries.
High Performance Liquid Chromatography Columns
Desired Partnerships
- License
- Sponsored Research
- Co-Development