Competitive Advantages
- Increases reproducibility
- Increases sensitivity
- Improves the sample preparation process
- Enhancement in the detection of molecular compounds
Summary
Our researchers have developed a technology that aims at increasing the reproducibility and sensitivity of MALDI-MS for water-insoluble matrix based samples through improving the sample preparation process. The invention introduces an additional feature to the anchor spot called nucleation enhancement via nanotubes. These nanotubes act as anchor surfaces for the water-insoluble matrix solution and concentrate a droplet to a specific position on a MALDI-MS sample plate. The nanotube spots show consistently better performance than the standard plate controlled samples. The enhancement may be achieved with other materials, such as semiconductor or insulator nanowires, or micro-machined/lithographically patterned three dimensional surface structures.
Scanning Electron Microscopy Images of the Carbon Nanotube Patch Used as Anchor Spot
Desired Partnerships
- License
- Sponsored Research
- Co-development